Selecting Experimental Parameters for Modulated DSC
Overview In this Tech Tip, we will give a general overview of the parameters you need to select when running a modulated differential scanning calorimetry experiment, also known as MDSC.
A Novel Thermodynamic Assay for Predicting and Monitoring Biomolecular Structure Stability
We performed a comparability study of a liquid protein reference formulation using a nano differential scanning calorimeter (Nano DSC) to reveal that this thermodynamic technology detects the smallest changes in biomolecular structure in response to subtle manipulations in the reference formulation.
Determining the Mechanical Properties of Non-Woven PLGA Scaffolds
To Characterize the Variation in Material Properties of Non-Woven PLGA Fibers
How to Improve Additive Manufacturing (3D printing) with Rheology
Successful additive manufacturing products depend upon your materials’ properties and behaviors. Rheology provides valuable information for safe, efficient, and reproducible polymer manufacturing.
Isothermal Microcalorimetry: Pharmaceutical Applications of Microcalorimetry
This application note will review the microcalorimetric techniques that are most commonly used within pharmaceutical science: including stability and compatibility tests, determination of small amounts of amorphic content and characterizing polymorphism.
Thermal Analysis of Polyamide 66 Gears with Added Recycle
In this note, the thermal properties of nylon gears with increasing mass fractions of recycled material are evaluated.
Powder Rheology of Lactose: Impacts of powder morphology on performance of pharmaceutical excipients
In this note, the processing behavior of two lactose excipients is studied by measuring shear and flowability of milled and spray-dried lactose. Milled lactose was found to have higher cohesion, yield strength, confined and unconfined flow energies when compared to spray-dried lactose.
Apparent Melting: A New Approach to Detecting Drug-Excipient Incompatibility
The purpose of this paper is to explain and illustrate a systematic thermal analysis approach (DSC, MDSC®, and TGA) for detecting drug-excipient incompatibility and then optionally exploring the rate of reaction (kinetics) and reaction mechanism (chemistry).
Characterization of Bio-Derived Polymer Under Controlled Humidity
In this apps note, the properties of PLA are studied under various controlled humidity and temperature conditions.
Using Rheology and Thermal Analysis to Help Optimize Processing Conditions of Recycled PET
his application note describes the importance of using thermal and rheological techniques to help fingerprinting the molecular architecture of the PET feedstocks.
Measurement of Glass Transition Temperatures by Dynamic Mechanical Analysis and Rheology
This note will detail the use of dynamic mechanical analysis (DMA) and rheology to characterize the glass transition of a polymeric material.
Thermal Degradation Study of Nylon 66 using Hyphenation Techniques TGA-MS and TGA-FTIR-GC/MS
In this work, the thermal degradation process of nylon 66 was studied using TGA-MS, TGA-FTIR and TGA-GC/MS in inert gas environments. These techniques together can provide a lot of insights of the thermal degradation process and its off-gas products.