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Microcalorimetry is a suite of techniques that measure enthalpy and heat capacity changes from chemical reactions or physical events. Microcalorimetry is used to monitor and analyze chemical, physical, and biological processes in real-time, making it a powerful technique for in-depth characterization of molecular binding events and structural stability. Researchers use microcalorimetry to optimize reactions and material compatibility in pharmaceuticals, chemicals, and batteries.
Microcalorimeters are instruments that measure very small quantities of heat. TA Instruments’ Isothermal Titration Calorimetry (ITC), Differential Scanning Calorimetry (DSC), and Isothermal Calorimetry systems measure a variety of molecular interactions with advanced technology for superior data accuracy. Microcalorimeters’ measurements inform thermodynamic binding signatures that reveal not only the strength of a binding event, but also the specific or nonspecific driving forces of the reaction.
The TA Instruments family of microcalorimeters provide the performance, reliability and ease-of-use required for the most demanding applications in drug discovery, biomolecular interactions, structure-function characterization, and more. The TAM Air, TAM IV, Affinity ITC, Nano ITC and Nano DSC offer industry-leading stability and sensitivity to evaluate structural stability profiles and reaction analysis. With our diverse line of instruments and accessories paired with unmatched global support, TA Instruments microcalorimeters are sure to exceed your expectations and enhance your discoveries.