Must Know Analytical Techniques for Biopharma Developers

eBook Must Know Analytical Techniques for Biopharma Developers A guide to pivotal analytical techniques for biopharmaceutical formulations and development Five takeaways you’ll learn from this eBook: Assess biopharmaceuticals qualitatively and quantitatively – including differentiation between conjugate types and drug-to-antibody ratios Determine ideal formulation conditions and identify changes during drug manufacturing or storage Gain a clear…

Determination of the Relative Oxidative Stability of Polyethylene Bottle Tops by Differential Scanning Calorimetry (DSC)

Oxidative degradation of polymers is an exothermic process (releases heat) and is detectable by differential scanning calorimetry (DSC). Furthermore, DSC evaluation of polyethylene at elevated temperatures in the presence of oxygen is an effective method for accelerating the onset of degradation so that longer term (shelf life) properties can be predicted and/or compared.

Advances in Native Binding Assays

Isothermal titration calorimetry is a technique where heat is measured under constant pressure. This heat can be translated into enthalpy based on the First Law of Thermodynamics. Although the focus of the technique has been rooted in measuring biophysical phenomena in labs that specialized in calorimetry, it has seen growth as a general technique to quantitatively describe systems from proteins to nanomaterials.