Monitoring DNA Melting using Nano DSC
In this application note, we used the Nano DSC to monitor ST-DNA melting at a range of concentrations in phosphate buffer.
Flexural Fatigue Behavior of Woven Fiberglass Composites at Elevated Temperature
This study investigates the influence of operating temperature on the flexural properties and fatigue life of two grades of Garolite woven fiberglass composites using an Electroforce 3330 load frame.
Must Know Analytical Techniques for Biopharma Developers
eBook Must Know Analytical Techniques for Biopharma Developers A guide to pivotal analytical techniques for biopharmaceutical formulations and development Five takeaways you’ll learn from this eBook: Assess biopharmaceuticals qualitatively and quantitatively – including differentiation between conjugate types and drug-to-antibody ratios Determine ideal formulation conditions and identify changes during drug manufacturing or storage Gain a clear…
Sustainable Tire Rubber – A Comparison of Silica and Carbon Black Filled Tread Compounds Using DMA
In this note, viscoelastic properties of SBR mixed with linear and branched butadiene, and carbon and silica filler are systematically investigated using dynamic mechanical analysis.
Introduction to Polymer Melt Rheology and its Application in Polymer Processing
Polymer melt rheology aims to understand and quantify the viscous and elastic properties of a polymer so that the process parameters are aligned with the material’s melt properties and vice-versa.
Comparison of Crystallization Behavior of Different Colored Parts Made from Polypropylene Using a Single DSC Experiment
This paper utilizes a single run DSC experiment and analysis of the crystallization data using the Avrami equation to obtain a cursory but useful comparison of crystallization characteristics of different colored polypropylene marker caps purchased from an office supply store.
Thermal Analysis Application Brief Oxidative Stability of Polyethylene Terephthalate
Differential scanning calorimetry (DSC) is an effective technique for rapidly evaluating the oxidative stability of polymers and enables fiber producers to determine optimum formulations.
Determination of the Relative Oxidative Stability of Polyethylene Bottle Tops by Differential Scanning Calorimetry (DSC)
Oxidative degradation of polymers is an exothermic process (releases heat) and is detectable by differential scanning calorimetry (DSC). Furthermore, DSC evaluation of polyethylene at elevated temperatures in the presence of oxygen is an effective method for accelerating the onset of degradation so that longer term (shelf life) properties can be predicted and/or compared.
“Apparent Melting”: A New Approach to Characterizing Crystalline Structure in Pharmaceutical Materials
The purpose of this paper is to provide a universally acceptable definition of “Melting” and then illustrate that loss of crystalline structure in many materials can be caused by numerous chemical processes other than thermodynamic or “True Melting”.
Isothermal Titration Calorimetry in Organic Solvent Systems
ITC has recently received increased attention from the field of material science, which necessitates the use of non-aqueous solvent systems. Herein, we elaborate on the development of a representative binding assay that measures the interactions of Ca2+ with a calcium ionophore in a methanol solvent system.
Determining Thermal Stability of Antibodies with a Nano DSC
The interaction between the antigen binding site and an antigen is extremely specific, which has made antibodies very highly desirable reagents when developing a wide variety of antigen detection assays.
Advances in Native Binding Assays
Isothermal titration calorimetry is a technique where heat is measured under constant pressure. This heat can be translated into enthalpy based on the First Law of Thermodynamics. Although the focus of the technique has been rooted in measuring biophysical phenomena in labs that specialized in calorimetry, it has seen growth as a general technique to quantitatively describe systems from proteins to nanomaterials.