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Key Analytical Techniques for Pharmaceutical Discovery and Formulation
eBook Pharmaceutical Discovery and Formulation eBook Download Key Analytical Techniques for Pharmaceutical Discovery and Formulation Pharmaceutical breakthroughs and successful development are facilitated by accurate material data. Material analysis helps pharmaceutical researchers ensure product stability, compatibility, and end use application. As a result, this information helps eliminate undesirable formulations early and accelerate time to market. Without…
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Kadine Mohomed – Characterization of Amorphous Pharmaceuticals by DSC Analysis
Kadine Mohomed – Characterization of Amorphous Pharmaceuticals by DSC Analysis The glass transition temperature of an amorphous pharmaceutical solid is a critical physical property that can greatly influence the material’s chemical stability, physical stability, and viscoelastic properties. Thankfully with specific analytical tests made possible through the use of Differential Scanning Calorimetry, this and other thermal…
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Jianqing Bennett Named Senior Vice President of TA Instruments
New Castle, Delaware, April 21, 2021 – On April 21, 2021, Waters Corporation announced that Jianqing Bennett was named to the post of Senior Vice President of TA Instruments Division, succeeding Jonathan Pratt who is now Senior Vice President of the Waters Division. Ms. Bennett most recently served as Senior Vice President, High Growth Markets…
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Jan Vermant – Orthogonal Superposition Rheology
Jan Vermant – Orthogonal Superposition Rheology OVERVIEW Superposition flows in rheology are powerful methods to understand non-linear and anisotropic viscoelasticity. Parallel Superposition experiments have been historically simple to perform, but are difficult to understand and do not provide all of the desired information. Recent developments have made Orthogonal Superposition more simple to perform, allowing…
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ITC Batch Analysis in NanoAnalyze
Overview In this Tech Tip, we will demonstrate the ITC Batch Analysis in NanoAnalyze.
DetailsIsothermal Titration Calorimetry in Organic Solvent Systems
ITC has recently received increased attention from the field of material science, which necessitates the use of non-aqueous solvent systems. Herein, we elaborate on the development of a representative binding assay that measures the interactions of Ca2+ with a calcium ionophore in a methanol solvent system.
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Isothermal Titration Calorimetry (ITC) for Binding Characterization in Pharmaceutical Research
Pharmaceutical research and discovery rely on accurate characterization of molecular interactions to develop effective and safe drugs. Isothermal Titration Calorimetry (ITC) is a gold-standard technique that provides critical insights into binding affinity, thermodynamics, and stoichiometry—essential components in Structure-Activity Relationship (SAR) studies.
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Isothermal Microcalorimetry: Pharmaceutical Applications of Microcalorimetry
This application note will review the microcalorimetric techniques that are most commonly used within pharmaceutical science: including stability and compatibility tests, determination of small amounts of amorphic content and characterizing polymorphism.
DetailsIsothermal Microcalorimetry to Monitor Bacteria Growth
There has been significant work done looking at using IMC to characterize the growth patterns of bacteria3-9 and even converting isothermal microcalorimetry data into biologically meaningful data such as growth rate, lag phase, or maximum growth.
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