Differential Scanning Calorimetry is a thermal analysis technique commonly used to characterize materials across a broad array of applications including chemistry, biochemistry, pharmaceuticals, polymers, and more. Differential Scanning Calorimetry (DSC) measures the heat flow in a material as it is heated or cooled over a specified temperature range.
A testament to the march of scientific inquiry, thermogravimetry emerged through the integration of three individual inventions in the 19th and 20th centuries: the electric furnace, the thermocouple, and the microbalance. As a cornerstone of material science, chemistry, and various other industries, thermogravimetric analysis (TGA) has since developed in leaps and bounds. Today, TA Instruments are leading the way in TGA, and we welcome you to join us as we explore the workings and applications of this groundbreaking technique.
Powders are a big part of everyday life, from baking and laundry to cosmetics and pharmaceuticals. Understanding powder rheology—how powders flow and deform—is crucial for optimizing their use in various applications. This knowledge helps industries maintain consistency and product quality.
Rheology is a notoriously complex field, combining mathematics and physics to characterize materials. For inexperienced users, rheology can seem like a massive challenge. Luckily, new technology simplifies rheology down to its core so you can get essential measurements without difficult training, measurements, or calculations.
Our world is brimming with viscoelastic materials: The dough you knead before baking a fresh loaf, the Silly Putty your toddler slaps against the wall, the rubber gaskets that create an airtight seal on an airplane door. Testing those materials by applying controlled deformations (strains) or forces (stresses) at various timescales, temperatures, and/or humidities allows for the optimization of properties and ensures durability and safety.
As a central pillar of modern society, the pharmaceutical industry bears the load of billions of lives around the world. In 2022, the global revenue of the pharmaceutical industry approximated $1.5 trillion, a figure reflected in two decades of significant growth.
Pharmaceutical development is highly regulated, and for good reason. Potential new products must be rigorously tested to ensure their safety, purity, and performance are acceptable before coming to market. For topical creams, regulations uphold stability lifetime parameters and require identification of any impurities before products reach consumers.
Lyophilization, also called freeze-drying, is the process of removing water from a sample, often for preservation. Lyophilization involves the sublimation of a sample’s water content, usually through a rapid freezing process. Freezing materials quickly helps avoid the destruction of the cell walls in the sample from the formation of large ice crystals.
Gene therapy is an approach to disease treatment where a patient’s genetic makeup is altered rather than using drugs or surgery. Gene therapy treatment is accomplished through the activation of a particular gene, repairing faulty genes, or introducing new genes to help fight disease.
Pharmaceutical development is highly regulated, and for good reason. Potential new products must be rigorously tested to ensure their safety, purity, and performance are acceptable before coming to market. For topical creams, regulations uphold stability lifetime parameters and require identification of any impurities before products reach consumers.
Differential scanning calorimetry is an analytical technique used to measure the amount of heat released or absorbed by a sample during heating or cooling over a range of temperature. As well as being used to characterize the thermal properties of a material, a differential scanning calorimeter is used to determine the temperature at which particular phase transitions occur, including glass transition temperature, fusion and crystallization events.