Antibody stability is crucial for antibody performance in therapeutics. High antibody thermostabilities are essential for creating products with a reasonable shelf life and avoiding problems with deterioration of the biophysical properties of the antibody.
Gene therapy is an approach to disease treatment where a patient’s genetic makeup is altered rather than using drugs or surgery. Gene therapy treatment is accomplished through the activation of a particular gene, repairing faulty genes, or introducing new genes to help fight disease.
Isothermal Titration Calorimetry (ITC) is an experimental method used to measure the amount of heat released or consumed during a bimolecular chemical reaction. Chemical reactions can be either exothermic or endothermic, depending on the relative energetic stabilities of the reactants. Isothermal titration calorimetry can be used to quantify the magnitude of the heat change during the reaction.
Biological macromolecules are fundamental components of every cell and are therefore essential for all life. These vital molecules are categorized into four major classes: carbohydrates, lipids, proteins, and nucleic acids. Characterizing biological macromolecules is important for understanding their functions and relationships, which empowers the development of new therapies and treatments. Under this branch of macromolecule research, biotherapeutic drug therapy focuses on macromolecular interactions which can lead to disease and/or cell death.