In this webinar, Dr. Colette Quinn discusses the use of differential scanning calorimetry (DSC) in protein stability characterization differences resulting from preparation changes of identical systems. Protein stability, particularly antibodies, can be determined via DSC without restrictions on buffers, excipients, and detergents. DSC, a native assay, works equally well for modified proteins such as antibody…
DetailsOverview Differential Scanning Calorimetry (DSC) is typically used during biopharmaceutical development to characterize a biomolecule through its thermal stability and unfolding profile. Here we demonstrate the suitability of DSC for studies of opaque solutions and slurries. Because of its universal indicator, heat, the technique can be applied to samples with magnetic or polystyrene beads,…
DetailsBiopharma Virtual Workshop Analytical Techniques Used to Gain Insight Needed to Bring Medicine and Technology to Market – Part 1: Binding, Unfolding, and Optimization – ITC Analytical Techniques Used to Gain Insight Needed to Bring Medicine and Technology to Market – Part 2: Binding, Unfolding, and Optimization – DSC Analytical Techniques Used to Gain Insight…
DetailsDrug development is a long and complex process that starts with discovery and, if successful, ends with government approval for marketing. Each step in the drug development process, outlined below, has specific goals with the aim of down-selecting appropriate hits and candidates to an approved drug substance.
DetailsWhite Paper Beyond the Spec Sheet: Revealing Polymer Structure and Properties Through Material Analysis Testing and Validating Polymer Strength and Durability for Real-World Applications As industries push for stronger, more durable materials in demanding applications like aerospace, automotive, and electronics, understanding polymer’s real-world performance beyond standard specification is crucial. Material selection usually begins with the…
DetailsBenefits of Microscopy for Interpretation of DSC Thermograms DSC thermograms can be complicated and difficult to interpret, sometimes requiring multiple experiments in order to better understand a thermal event. The NEW Microscope Accessory for the Discovery DSC helps to eliminate these issues by allowing the user to easily view the sample while the DSC experiment…
DetailsGuide Battery Testing Selection Guide A Selection Guide for Analytical Solutions Unlocking the Full Potential of Batteries Cutting-Edge Analytical Solutions for the Next Generation of Battery Development The race for the next generation of battery technology is well underway. In just a few decades, rechargeable batteries have grown well beyond their roots in consumer electronics…
DetailsGuide Battery Testing Selection Guide A Selection Guide for Analytical Solutions The race for the next generation of battery technology is well underway. Battery developers are tasked with optimizing batteries for existing applications – like higher energy density and improved safety for electric vehicles – or innovating new formulations to overcome challenges such as lithium…
DetailsThis note applies the workflow outlined in TA457 [3] to characterize coated and uncoated separators. In addition to TMA, differential scanning calorimetry (DSC), thermogravimetric analysis (TGA), and dynamic mechanical analysis (DMA) will be utilized.
DetailsIn battery development, precise rheological measurements are critical for optimizing material performance, ensuring uniform coatings, and enhancing conductivity. Whether working with cathode, anode, or electrolyte materials, selecting the right rheometer is essential. TA Instruments offers two industry-leading solutions: the Discovery Core Rheometer and the Discovery Hybrid Rheometer. This guide helps battery scientists determine which instrument best suits their needs.
DetailsPoster Optimize Battery Electrode Slurry Behavior with Rheology Optimizing electrode slurries offers significant returns in streamlining manufacturing and improving battery performance. Properly designing your slurry formulation and mix conditions can lead to smoother, cost-effective processing. Additionally, a slurry’s shelf life and stability are important factors for ensuring reliable battery function. This poster illustrates four key…
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