Unlock a New Dimension in your Battery Research Through Isothermal Microcalorimetry
Overview In order to meet growing market demands for power storage, Lithium ion and new battery chemistries demand higher energy density, longer cycle life, calendar life, and better safety to a lower cost. Isothermal microcalorimetry is a highly sensitive, non-destructive and non-specific tool to characterize these critical performance criteria. Learn how this method provides:…
Elucidating Thermodynamic Details of Biologic and Small Molecule Drugs using Microcalorimetry
Overview Researchers are working tirelessly to understand the basic chemical details of viral pathogenesis, viral protein structures, and identifying therapeutics to disrupt and prevent disease. There are different modes of therapies evolving that include small-molecule antiviral drugs, mRNA, and protein-based vaccines. Microcalorimetry is one powerful tool for the development and characterization of the mechanism of…
Chemical Characterization of Medical Devices
Overview You will gain insight into the role of chemical characterization in newly modified EU Medical Device Regulations (EU MDR) impacting ISO 10993. This webinar highlights how you can leverage HRMS to overcome characterization challenges.
Microcalorimetric Testing of Biomedical Devices | Medical Devices Webinar Series
Overview This webinar addresses microcalorimetric testing can shed light on the effects of coatings and sterilization on material stability and how it can support the overall study of the rate, extent, and prevention of cell adhesion.
Biophysical Characterization of Antibodies in a Suspension: Solutions for Slurries
Overview Differential Scanning Calorimetry (DSC) is typically used during biopharmaceutical development to characterize a biomolecule through its thermal stability and unfolding profile. Here we demonstrate the suitability of DSC for studies of opaque solutions and slurries. Because of its universal indicator, heat, the technique can be applied to samples with magnetic or polystyrene beads,…
Applications for Isothermal Heatflow Calorimetry – Lithium Ion Battery Chemistry
Overview It is now well established that the calendar life and cycle life of Li and Li-ion cells and batteries is highly dependent upon the secondary reactions that occur between the electrodes and the cell electrolyte. These reactions are often referred to as parasitic reactions, as they generally result in the loss of…
Isothermal Microcalorimetry in Pharmaceutical Science
Isothermal Microcalorimetry in Pharmaceutical Science This webinar will review the microcalorimetric techniques that are most commonly used within pharmaceutical science, including stability and compatibility tests, determination of small amounts of amorphic content, and characterizing polymorphism. A microcalorimeter can quantify the amount and rate of heat release from chemical processes associated with stability and shelf…
Biophysical Characterization of Antibody Drug Conjugates Using DSC
In this webinar, Dr. Colette Quinn discusses the use of differential scanning calorimetry (DSC) in protein stability characterization differences resulting from preparation changes of identical systems. Protein stability, particularly antibodies, can be determined via DSC without restrictions on buffers, excipients, and detergents. DSC, a native assay, works equally well for modified proteins such as antibody…
Long Term Stability Analysis of Monoclonal Antibodies
Long Term Stability Analysis of Monoclonal Antibodies Overview Characterization of biopharmaceuticals during all development phases is critical to the candidate selection process and the ongoing production of the active material. Some recent efforts to achieve patient self-administration has required high API concentrations (100-300 mg/mL). Development concerns for the high concentration formulations are denaturation, aggregation…