Getting the Rheology Right for Generic Topical Pharma Submissions
Summary For any generic pharmaceutical developer submitting a new drug application, the process of demonstrating the equivalence of a topical pharmaceutical to a reference listed drug can be a grueling process. Not least of the challenges facing regulatory affairs personnel is navigating the often-daunting landscape of rheological measurements. Agencies such as the FDA and EMA…
Comprehensive Rheological Characterization to Optimize Electrode Manufacturing
Summary Electrode manufacturing for lithium-ion batteries is a complex, multistep process that requires comprehensive material characterization to ensure quality and consistency in the final electrodes. Electrode processing involves combining active materials with binders and conductive additives to form a coating on the current collector, either as a slurry or dry coating. The mixing and coating…
How to Expand Your High-Performance Rheometer Capabilities for Powder Characterization
Summary Research rheometers present excellent platforms for the characterisation and quantification of powder flowability. Until recent years, powder characterisations have been restricted only to instruments dedicated to just that one class of materials. Now there is a growing recognition of the opportunities for extending the application of high-performance rheometers to the measurement of particulate solids.…
Strategies for Rheological Evaluation of Adhesives
Overview Adhesives are widely used across a broad range of industries and are a regular part of consumers’ daily lives. A quantitative understanding of the performance of such materials, such as adhesion, cohesion, tack, and peel performance is important for quality control and guiding formulators. Rheology is a powerful tool that provides direct measurement…
Catalysis R&D with High Pressure Thermogravimetry – Instruments and Applications
Overview Catalytic reactions are of tremendous commercial importance. Over 90% of all chemicals worldwide are manufactured with the aid of solid catalysts. Developing improved catalysts and optimizing the reaction conditions are key for improving commercial and ecological efficiency of catalytic processes. High-pressure thermogravimetric analysis (HP-TGA) allows investigating reactions of a catalyst with the gas…
Melt Viscosity Measurements at High Temperatures
Overview Maintaining the optimum viscosity of a molten material is key for efficiency and product quality of many industrial processes. Processing of melts at high temperatures is the basis for classical or additive manufacturing of many materials like glasses or metals. Molten slag or ash viscosity is essential for economically operating industrial gasification processes…