Isothermal Microcalorimetry in Pharmaceutical Science

Isothermal Microcalorimetry in Pharmaceutical Science This webinar will review the microcalorimetric techniques that are most commonly used within pharmaceutical science, including stability and compatibility tests, determination of small amounts of amorphic content, and characterizing polymorphism. A microcalorimeter can quantify the amount and rate of heat release from chemical processes associated with stability and shelf…

Interfacial Rheology: Fundamental Overview and Applications

Interfacial Rheology: Fundamental Overview and Applications Overview Interfacial rheology dominates the behavior of many complex fluid systems. Whether the system is characterized by a fluid-fluid interface or fluid-air interface, these characteristics influence the behavior of biological systems, oil recovery, personal care products, food and more. Learn the basic forces that drive interfacial dynamics and…

Biophysical Characterization of Antibody Drug Conjugates Using DSC

Biophysical Characterization of Antibody Drug Conjugates Using DSC   In this webinar, Dr. Colette Quinn discusses the use of differential scanning calorimetry (DSC) in protein stability characterization differences resulting from preparation changes of identical systems. Protein stability, particularly antibodies, can be determined via DSC without restrictions on buffers, excipients, and detergents. DSC, a native…

Designing New Materials for Additive Manufacturing: Vat Photopolymerization

Designing New Materials for Additive Manufacturing: Vat Photopolymerization Overview 3D printing, or additive manufacturing (AM), provides opportunities to create previously unattainable geometric objects through layer-by-layer fabrication. Novel macromolecular structures and synthetic methods coupled with unique printing methods lead to 3D part generation with micron-scale resolution and tunable to emerging technologies. By tuning polymer structure,…

Long Term Stability Analysis of Monoclonal Antibodies

Long Term Stability Analysis of Monoclonal Antibodies Overview Characterization of biopharmaceuticals during all development phases is critical to the candidate selection process and the ongoing production of the active material. Some recent efforts to achieve patient self-administration has required high API concentrations (100-300 mg/mL). Development concerns for the high concentration formulations are denaturation, aggregation…

Stability Testing of Energetic Materials by Isothermal Microcalorimetry

Stability Testing of Energetic Materials by Isothermal Microcalorimetry Overview This webinar introduces the use of isothermal microcalorimetry for stability measurement of energetic materials. Energetic materials refer to materials, chemicals and substances which exhibit a risk for self-decomposition associated with self-heating ultimately resulting in run-way reactions. Such materials include propellants, percarbonates and peroxides, and these…

Chris Yakacki: Characterization of Active Shape-Memory Polymers

Chris Yakacki: Characterization of Active Shape-Memory Polymers   The field of stimuli-sensitive polymers has grown rapidly over the past decade. Actively-moving polymers have gained attention and have been proposed for use in applications from shape-changing biomedical devices to morphing structures. This webinar covers the basics of characterizing shape-memory polymers using thermo-mechanical equipment, such as the Q800…

An Introduction To High Pressure Rheology

An Introduction To High Pressure Rheology High pressure rheology explores phenomena that are not accessible at ambient laboratory conditions. Three of the advantages of using a pressure rheometer cell include a controlled environment for volatile fluids, saturating fluids with soluble constituents, and exploring new phase space using a combination of temperature and pressure.

Rubber Process Analyzer (RPA) for Elastomer and Compound Development and Quality Control

Rubber Process Analyzer (RPA) for Elastomer and Compound Development and Quality Control The Rubber Process Analyzer (RPA) is an important tool for developing – and controlling the reliable manufacture of – elastomers and compounds. The RPA can provide far more information than traditional rubber testing methods such as the MDR or Mooney viscometer. In this…

Dile Holton, Ph.D.: Characterization of Drug Binding Activity and Biopharmaceutical Stability

Dile Holton, Ph.D.: Characterization of Drug Binding Activity and Biopharmaceutical Stability This webinar is focused on enthalpy screening, a new and recently published ITC technique that is showing promise for rapidly and accurately characterizing the binding enthalpy of new drugs or biotherapeutics. Rapid and accurate characterization of biopharmaceuticals is essential for the early selection of…