Rheology, Easy as Pie
I love a good experiment in the kitchen, especially when it involves baking and desserts. In celebration of Pi Day, let’s take science and experiments into the kitchen with pie dough and fillings…and a rheometer.
Advance Formulation Performance with Rheology Studies
The progression from formulation development to commercial formulation is dependent on the dose strength, intrinsic stability, and extent of protein self-association in the final drug.1 This is because the drug is reaching the final stage of development.
Optimizing Formulations After Candidate Selection
Candidate selection is the third phase of the drug development process. The main purpose of candidate selection is to continue screening and filtering down to the most promising antibodies, ideally having one or two progress forward. During this phase, researchers are looking to evaluate the developability of a pool of less than five antibodies.
Applying Dynamic Mechanical Analysis (DMA) to Test the Durability of Protective Sports Equipment
There is a renewed interest in the durability of protective sports equipment after Patrick Mahomes’ helmet recently cracked apart in -4 degrees Fahrenheit (-20 degrees Celsius) weather. Scientists from TA Instruments ran tests to find out if materials found in protective sports equipment can break due to cold weather.
Thermal Analysis for Printed Circuit Boards (PCBs)
Printed circuit boards (PCBs) form the backbone of virtually all electronic applications. Enhancing their performance and reliability is paramount for custom PCB projects, where smaller footprints and improved maintainability lead to enhanced functionality.
How to Assess Binding in Drug Discovery
The most popular tool used to characterize binding in the late-discovery phase of drug development is isothermal titration calorimetry (ITC). ITC is a high-resolution method for complete characterization of the basic chemical details of a binding interaction. The calorimeters accomplish this by measuring the heat that is released or absorbed when molecules interact with each other.
Using Rheology to Determine the Perfect Viscosity of Gravy
On holiday tables across the world, an unexpected unsung hero can make or break the meal: gravy. The seemingly simple condiment adds a dash of flavor to the star roast, livens up potatoes, and can rescue even the driest turkey that may accidentally make its way to the table.
4 Polymer Insights from Dynamic Mechanical Analysis
From material selection and failure analysis to end-use application, Dynamic Mechanical Analysis (DMA) offers crucial polymer insights. Polymer scientists and design engineers pair DMA with fatigue testing to gain a complete view of their material’s properties and performance attributes.
BioPharma Drug Development Workflow and Techniques
Drug development is a long and complex process that starts with discovery and, if successful, ends with government approval for marketing. Each step in the drug development process, outlined below, has specific goals with the aim of down-selecting appropriate hits and candidates to an approved drug substance.
History of Microcalorimetry
Throughout the 18th century, many scientists questioned the nature of heat. Isaac Newton thought that heat was transferred by the vibrations of particles, while Robert Hooke believed heat was a property of the body that arose from the motion of its parts.
Material Analysis of Composites
We expect a lot from our composites: rocket materials need to endure the heat of takeoff, wind turbines must withstand high wind gusts, and sneakers are expected to be durable and supportive on long runs. How do experts develop composites tailored to such specific uses and verify their properties?
How to Optimize Battery Electrode Slurries with Rheology
From lightweight laptops to cross-country EV driving, countless applications require increasing lithium-ion batteries’ energy density and performance. Since battery electrodes directly contribute to these aspects of battery function, electrodes and their components are of particular interest to battery researchers seeking to advance technology to the next level. Battery slurry processing is also a key step of manufacturing, offering significant opportunities to increase efficiency while reducing cost.