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Biophysical Characterization of Antibody Drug Conjugates Using DSC

Biophysical Characterization of Antibody Drug Conjugates Using DSC   In this webinar, Dr. Colette Quinn discusses the use of differential scanning calorimetry (DSC) in protein stability characterization differences resulting from preparation changes of identical systems. Protein stability, particularly antibodies, can be determined via DSC without restrictions on buffers, excipients, and detergents. DSC, a native…

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DSC Characterization of Crystalline Structure in Foods and Pharmaceuticals (Part 1 of 3)

DSC Characterization of Crystalline Structure in Foods and Pharmaceuticals Part 1 Overview The determination of the crystalline structure that exists in a pharmaceutical material is critical to fully understanding the inherent properties of the resultant drug. The crystal structure can influence the drug’s properties, such as stability and dissolution rates, as well as impact the…

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Designing New Materials for Additive Manufacturing: Vat Photopolymerization

Designing New Materials for Additive Manufacturing: Vat Photopolymerization Overview 3D printing, or additive manufacturing (AM), provides opportunities to create previously unattainable geometric objects through layer-by-layer fabrication. Novel macromolecular structures and synthetic methods coupled with unique printing methods lead to 3D part generation with micron-scale resolution and tunable to emerging technologies. By tuning polymer structure,…

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TA Instruments Announces new Saudi Arabia distributor

TA Instruments Announces new Saudi Arabia distributor New Castle, Delaware, USA. January 30, 2018 TA Instruments is pleased to announce Integrated Modern Scientific Supplies – Gulf Bio Analytical Group of Companies (IMSS-GBA) as the new exclusive distributor for Saudi Arabia: (http://www.gulfbioanalytical.com/ta-instruments-thermal-analysis/). ‘’IMSS-GBA is very excited to be appointed as sole distributor of TA Instruments in the…

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Long Term Stability Analysis of Monoclonal Antibodies

Long Term Stability Analysis of Monoclonal Antibodies Overview Characterization of biopharmaceuticals during all development phases is critical to the candidate selection process and the ongoing production of the active material. Some recent efforts to achieve patient self-administration has required high API concentrations (100-300 mg/mL). Development concerns for the high concentration formulations are denaturation, aggregation…

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