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Getting the Rheology Right for Generic Topical Pharma Submissions

Summary For any generic pharmaceutical developer submitting a new drug application, the process of demonstrating the equivalence of a topical pharmaceutical to a reference listed drug can be a grueling process. Not least of the challenges facing regulatory affairs personnel is navigating the often-daunting landscape of rheological measurements. Agencies such as the FDA and EMA…

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Gerald Fuller – Interfacial Rheology

Gerald Fuller – Interfacial Rheology OVERVIEW Interfacial rheology dominates the behavior of many complex fluid systems. Whether the system is characterized by a fluid-fluid interface or fluid-air interface, these characteristics influence the behavior of biological systems, oil recovery, personal care products, food and more. Learn about the basic forces that drive interfacial dynamics and stability,…

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Gareth H. McKinley – Rheological Fingerprinting of Complex Fluids

OVERVIEW Large amplitude oscillatory shear (LAOS) is used increasingly as a tool to measure the nonlinear viscoelastic responses of soft solids and complex fluids. For many material systems the common practice of reporting only “viscoelastic moduli” (typically corresponding to the first harmonic Fourier coefficients G’1(w), G”1(w)) is insufficient and/or misleading in describing the nonlinear phenomena.…

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