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Hyphenation of Thermogravimetric Analyzers with FTIR, MS, and GC-MS Instruments

  Overview Thermogravimetric Analysis, or TGA, is a powerful analytical tool for measuring changes in a sample’s mass as its environmental temperature shifts. When coupled with other instrumental techniques such as mass spectrometers and infrared spectrometers, chemical analysis of the evolved gases is achieved. These hyphenated techniques have a long history in thermal analysis.…

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In Search of Calorimetric Answers to Events In Self Assemblies

In Search of Calorimetric Answers to Events In Self Assemblies In this TA Webinar, Professor Nand Kishore discusses how to best discover and interpret protein folding, ligand binding, aggregation and molecular partitioning in self assemblies. Isothermal titration (ITC) and differential scanning calorimetry (DSC) are powerful tools for thermodynamic characterization of protein folding intermediates, drug-protein…

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Interfacial Rheology: Fundamental Overview and Applications

Interfacial Rheology: Fundamental Overview and Applications Overview Interfacial rheology dominates the behavior of many complex fluid systems. Whether the system is characterized by a fluid-fluid interface or fluid-air interface, these characteristics influence the behavior of biological systems, oil recovery, personal care products, food and more. Learn the basic forces that drive interfacial dynamics and…

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Introducing the New TAM Air Isothermal Calorimeter

Introducing the New TAM Air Isothermal Calorimeter This webinar introduces the all-new TAM Air Isothermal Calorimeter. Delivering the performance, reliability, and ease-of-use that is the hallmark of TA Instruments products, the new TAM Air maintains its leadership position as the instrument of choice for cement and concrete hydration analysis using ASTM C1702 and C1679, as…

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Isothermal Microcalorimetry in Pharmaceutical Science

Isothermal Microcalorimetry in Pharmaceutical Science This webinar will review the microcalorimetric techniques that are most commonly used within pharmaceutical science, including stability and compatibility tests, determination of small amounts of amorphic content, and characterizing polymorphism. A microcalorimeter can quantify the amount and rate of heat release from chemical processes associated with stability and shelf…

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Jan Vermant – Orthogonal Superposition Rheology

Jan Vermant – Orthogonal Superposition Rheology OVERVIEW Superposition flows in rheology are powerful methods to understand non-linear and anisotropic viscoelasticity. Parallel Superposition experiments have been historically simple to perform, but are difficult to understand and do not provide all of the desired information. Recent developments have made Orthogonal Superposition more simple to perform, allowing…

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Kadine Mohomed – Characterization of Amorphous Pharmaceuticals by DSC Analysis

Kadine Mohomed – Characterization of Amorphous Pharmaceuticals by DSC Analysis The glass transition temperature of an amorphous pharmaceutical solid is a critical physical property that can greatly influence the material’s chemical stability, physical stability, and viscoelastic properties. Thankfully with specific analytical tests made possible through the use of Differential Scanning Calorimetry, this and other thermal…

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Long Term Stability Analysis of Monoclonal Antibodies

Long Term Stability Analysis of Monoclonal Antibodies Overview Characterization of biopharmaceuticals during all development phases is critical to the candidate selection process and the ongoing production of the active material. Some recent efforts to achieve patient self-administration has required high API concentrations (100-300 mg/mL). Development concerns for the high concentration formulations are denaturation, aggregation…

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Measuring the Influence of Humidity on Material Properties

  Overview The impact of humidity on a material’s properties and performance during processing, storage, and in final form is a growing area of interest for manufacturers across many industries. A few areas of investigation of this impact include material selection and failure analysis of layered materials used with electronic circuit boards, morphological changes in…

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Measuring Thermodynamic Parameters in the Drug Development Process

Measuring Thermodynamic Parameters in the Drug Development Process Is there a benefit to measuring thermodynamic parameters in the drug development process? In this TA Instruments Webinar, Dr. John E. Ladbury discusses Thermodynamic Parameterization of protein-ligand interaction, not only provides quantification of the affinity of an interaction, but also the underlying changes in enthalpy and entropy.…

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