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Applications for Isothermal Heatflow Calorimetry – Lithium Ion Battery Chemistry
Overview It is now well established that the calendar life and cycle life of Li and Li-ion cells and batteries is highly dependent upon the secondary reactions that occur between the electrodes and the cell electrolyte. These reactions are often referred to as parasitic reactions, as they generally result in the loss of…
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Biophysical Characterization of Antibodies in a Suspension: Solutions for Slurries
Overview Differential Scanning Calorimetry (DSC) is typically used during biopharmaceutical development to characterize a biomolecule through its thermal stability and unfolding profile. Here we demonstrate the suitability of DSC for studies of opaque solutions and slurries. Because of its universal indicator, heat, the technique can be applied to samples with magnetic or polystyrene beads,…
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Biophysical Characterization of Antibody Drug Conjugates Using DSC
In this webinar, Dr. Colette Quinn discusses the use of differential scanning calorimetry (DSC) in protein stability characterization differences resulting from preparation changes of identical systems. Protein stability, particularly antibodies, can be determined via DSC without restrictions on buffers, excipients, and detergents. DSC, a native assay, works equally well for modified proteins such as antibody…
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Chemical Characterization of Medical Devices
Overview You will gain insight into the role of chemical characterization in newly modified EU Medical Device Regulations (EU MDR) impacting ISO 10993. This webinar highlights how you can leverage HRMS to overcome characterization challenges.
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Dile Holton, Ph.D.: Characterization of Drug Binding Activity and Biopharmaceutical Stability
Dile Holton, Ph.D.: Characterization of Drug Binding Activity and Biopharmaceutical Stability This webinar is focused on enthalpy screening, a new and recently published ITC technique that is showing promise for rapidly and accurately characterizing the binding enthalpy of new drugs or biotherapeutics. Rapid and accurate characterization of biopharmaceuticals is essential for the early selection of…
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ElectroForce Apex 1: Mechanical Testing Instrument Product Demonstration
Mechanical testing is a standard practice among top laboratories and manufacturers to support material selection, design decisions, component evaluation, and product performance validation. The TA ElectroForce Apex 1 Instrument seamlessly blends user-friendly design with enhanced motor technology, setting a new standard in advanced mechanical testing.
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Elucidating Thermodynamic Details of Biologic and Small Molecule Drugs using Microcalorimetry
Overview Researchers are working tirelessly to understand the basic chemical details of viral pathogenesis, viral protein structures, and identifying therapeutics to disrupt and prevent disease. There are different modes of therapies evolving that include small-molecule antiviral drugs, mRNA, and protein-based vaccines. Microcalorimetry is one powerful tool for the development and characterization of the mechanism of…
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