Overview It is now well established that the calendar life and cycle life of Li and Li-ion cells and batteries is highly dependent upon the secondary reactions that occur between the electrodes and the cell electrolyte. These reactions are often referred to as parasitic reactions, as they generally result in the loss of…
DetailsOverview Differential Scanning Calorimetry (DSC) is typically used during biopharmaceutical development to characterize a biomolecule through its thermal stability and unfolding profile. Here we demonstrate the suitability of DSC for studies of opaque solutions and slurries. Because of its universal indicator, heat, the technique can be applied to samples with magnetic or polystyrene beads,…
DetailsBiophysical Characterization of Antibody Drug Conjugates Using DSC In this webinar, Dr. Colette Quinn discusses the use of differential scanning calorimetry (DSC) in protein stability characterization differences resulting from preparation changes of identical systems. Protein stability, particularly antibodies, can be determined via DSC without restrictions on buffers, excipients, and detergents. DSC, a native…
DetailsOverview You will gain insight into the role of chemical characterization in newly modified EU Medical Device Regulations (EU MDR) impacting ISO 10993. This webinar highlights how you can leverage HRMS to overcome characterization challenges.
DetailsDile Holton, Ph.D.: Characterization of Drug Binding Activity and Biopharmaceutical Stability This webinar is focused on enthalpy screening, a new and recently published ITC technique that is showing promise for rapidly and accurately characterizing the binding enthalpy of new drugs or biotherapeutics. Rapid and accurate characterization of biopharmaceuticals is essential for the early selection of…
DetailsOverview Researchers are working tirelessly to understand the basic chemical details of viral pathogenesis, viral protein structures, and identifying therapeutics to disrupt and prevent disease. There are different modes of therapies evolving that include small-molecule antiviral drugs, mRNA, and protein-based vaccines. Microcalorimetry is one powerful tool for the development and characterization of the mechanism of…
DetailsIn Search of Calorimetric Answers to Events In Self Assemblies In this TA Webinar, Professor Nand Kishore discusses how to best discover and interpret protein folding, ligand binding, aggregation and molecular partitioning in self assemblies. Isothermal titration (ITC) and differential scanning calorimetry (DSC) are powerful tools for thermodynamic characterization of protein folding intermediates, drug-protein…
DetailsIntroducing the New TAM Air Isothermal Calorimeter This webinar introduces the all-new TAM Air Isothermal Calorimeter. Delivering the performance, reliability, and ease-of-use that is the hallmark of TA Instruments products, the new TAM Air maintains its leadership position as the instrument of choice for cement and concrete hydration analysis using ASTM C1702 and C1679, as…
DetailsIntroducing the new TAM IV & TAM IV-48 Microcalorimeters The new TAM IV is the world’s most sensitive, stable, and flexible microcalorimeter system. It is completely modular and combines the highest heat flow sensitivity with unmatched long-term temperature stability to measure processes that are undetectable by other techniques.
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