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Getting the Rheology Right for Generic Topical Pharma Submissions

Summary For any generic pharmaceutical developer submitting a new drug application, the process of demonstrating the equivalence of a topical pharmaceutical to a reference listed drug can be a grueling process. Not least of the challenges facing regulatory affairs personnel is navigating the often-daunting landscape of rheological measurements. Agencies such as the FDA and EMA…

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Comprehensive Rheological Characterization to Optimize Electrode Manufacturing

Summary Electrode manufacturing for lithium-ion batteries is a complex, multistep process that requires comprehensive material characterization to ensure quality and consistency in the final electrodes. Electrode processing involves combining active materials with binders and conductive additives to form a coating on the current collector, either as a slurry or dry coating. The mixing and coating…

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Rheology of Coatings and Inks

Rheology of Coatings and Inks Coatings and inks are two of the most common structured fluids that are characterized on rotational rheometers. Rheometers offer experimentalists many opportunities to perform selected tests that can reveal information about the properties of the fluids and allow one to predict the processability of these systems. Of particular interest are…

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Catalysis R&D with High Pressure Thermogravimetry – Instruments and Applications

  Overview Catalytic reactions are of tremendous commercial importance. Over 90% of all chemicals worldwide are manufactured with the aid of solid catalysts. Developing improved catalysts and optimizing the reaction conditions are key for improving commercial and ecological efficiency of catalytic processes. High-pressure thermogravimetric analysis (HP-TGA) allows investigating reactions of a catalyst with the gas…

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Melt Viscosity Measurements at High Temperatures

  Overview Maintaining the optimum viscosity of a molten material is key for efficiency and product quality of many industrial processes. Processing of melts at high temperatures is the basis for classical or additive manufacturing of many materials like glasses or metals. Molten slag or ash viscosity is essential for economically operating industrial gasification processes…

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Applications of Tribo Rheometry in Material Characterization

  Overview Tribology is the study of friction between two interacting surfaces. Traditionally encompassing friction-based studies of lubrication and wear, the applications of this field has expanded into different industries such as food and beverage (e.g: quantify mouthfeel and texture), personal care (e.g: quantify skin-feel), asphalt (e.g: development of warm mix asphalt technologies) and rubbers…

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