Rheology Theory and Applications
Will my paint coat the wall or drip off? Will my topical pharmaceutical spread on skin or form clumps? Rheology answers vital questions to inform how we create and interact with materials on a daily basis.
Rheologie, kinderleicht gemacht
Ich experimentiere gern in der Küche, besonders wenn es um Backen und Desserts geht. Zur Feier des Pi-Tages bringen wir Wissenschaft und Experimente in die Küche – mit einem Mürbeteig und Füllungen … und einem Rheometer.
Prüfung von Batterie-Slurrys durch gleichzeitige Rheologie- und Impedanzmessung
Lithium-Ionen-Batterien (LIB) werden in einem mehrstufigen Prozess hergestellt, bei dem verschiedene aktive und inaktive Materialien kombiniert werden. Materialauswahl und Verarbeitungsbedingungen können die Leistung der fertigen Batterie stark beeinflussen.
Verbesserung der Formulierungsleistung durch Rheologie-Analysen
Der Weg von der Entwicklung einer Formulierung hin zur kommerziellen Formulierung hängt von der Dosisstärke, der intrinsischen Stabilität und dem Ausmaß der Proteinselbstassoziation im fertigen Arzneimittel ab, wenn das Arzneimittel das Endstadium der Entwicklung erreicht.1
3 Essential Types of Mechanical Testing for Polymer Development
High-performance polymers are a critical material for manufacturers due to their combination of mechanical, thermal, and chemical properties, but especially their cost. Without adequate testing, manufacturers could run into a slew of issues, from immediate product failure to poor performance or failure after some time in usage.
Unlocking Stability: The Crucial Role of Thermal Analysis in Lyophilization Temperature Optimization
The method of drug delivery significantly influences the final stages of the manufacturing process. Currently, lyophilization—a widely adopted technique—enables drug developers to stabilize formulations and therapeutic molecules using a validated commercial approach. In this process, precise control of pressure and temperature within a lyophilizer facilitates the removal of liquids from formulations containing thermally sensitive or hydrolytically unstable active pharmaceutical ingredients or formulation components.
Characterization Considerations when Sourcing PCR
Against the backdrop of a plastic waste crisis, the global demand for plastic is set to quadruple by 2060. This has driven a shift toward sustainability and away from linear use models of plastic production. Post-consumer resin (PCR) has emerged as a key player in circular economy initiatives, though ensuring the quality and performance of PCR requires several characterization considerations.
Thermal Analysis in Pharmaceutical Research, Development, and Quality Control
As a central pillar of modern society, the pharmaceutical industry bears the load of billions of lives around the world. In 2022, the global revenue of the pharmaceutical industry approximated $1.5 trillion, a figure reflected in two decades of significant growth.
Thermische Analyse von Leiterplatten
Leiterplatten (Printed Circuit Boards, PCBs) bilden das Rückgrat praktisch aller elektronischen Anwendungen.
Beurteilung von Bindungseigenschaften in der Wirkstoffforschung
The most popular tool used to characterize binding in the late-discovery phase of drug development is isothermal titration calorimetry (ITC). ITC is a high-resolution method for complete characterization of the basic chemical details of a binding interaction. The calorimeters accomplish this by measuring the heat that is released or absorbed when molecules interact with each other.
4 Polymer Insights from Dynamic Mechanical Analysis
From material selection and failure analysis to end-use application, Dynamic Mechanical Analysis (DMA) offers crucial polymer insights. Polymer scientists and design engineers pair DMA with fatigue testing to gain a complete view of their material’s properties and performance attributes.
Arbeitsabläufe und Techniken bei der Entwicklung von Biopharmaka
Drug development is a long and complex process that starts with discovery and, if successful, ends with government approval for marketing. Each step in the drug development process, outlined below, has specific goals with the aim of down-selecting appropriate hits and candidates to an approved drug substance.