Long Term Stability Analysis of Monoclonal Antibodies

Long Term Stability Analysis of Monoclonal Antibodies Overview Characterization of biopharmaceuticals during all development phases is critical to the candidate selection process and the ongoing production of the active material. Some recent efforts to achieve patient self-administration has required high API concentrations (100-300 mg/mL). Development concerns for the high concentration formulations are denaturation, aggregation and…

Strategies for Rheological Evaluation of Adhesives

Strategies for Rheological Evaluation of Adhesives Overview Adhesives are widely used in industries and by consumers. A quantitative understanding of the physical performance of such materials, such as adhesiveness, cohesiveness, tack, and peel performance, are important for quality control and for guiding formulators. Rheology is a powerful tool that provides direct measurement of a material’s…