The most popular tool used to characterize binding in the late-discovery phase of drug development is isothermal titration calorimetry (ITC). ITC is a high-resolution method for complete characterization of the basic chemical details of a binding interaction. The calorimeters accomplish this by measuring the heat that is released or absorbed when molecules interact with each other.
DetailseBook How Material Selection Can Make or Break Your PCB Printed circuit boards (PCBs) are the foundation for most of today’s electronic devices. Developers need to bear in mind a variety of considerations, including production standards, material impact on performance, and application conditions. This eBook examines some of the critical issues PCB developers face and…
DetailsOn holiday tables across the world, an unexpected unsung hero can make or break the meal: gravy. The seemingly simple condiment adds a dash of flavor to the star roast, livens up potatoes, and can rescue even the driest turkey that may accidentally make its way to the table.
DetailsFrom material selection and failure analysis to end-use application, Dynamic Mechanical Analysis (DMA) offers crucial polymer insights. Polymer scientists and design engineers pair DMA with fatigue testing to gain a complete view of their material’s properties and performance attributes.
DetailsDrug development is a long and complex process that starts with discovery and, if successful, ends with government approval for marketing. Each step in the drug development process, outlined below, has specific goals with the aim of down-selecting appropriate hits and candidates to an approved drug substance.
DetailsThroughout the 18th century, many scientists questioned the nature of heat. Isaac Newton thought that heat was transferred by the vibrations of particles, while Robert Hooke believed heat was a property of the body that arose from the motion of its parts.
DetailsSummary Research rheometers present excellent platforms for the characterisation and quantification of powder flowability. Until recent years, powder characterisations have been restricted only to instruments dedicated to just that one class of materials. Now there is a growing recognition of the opportunities for extending the application of high-performance rheometers to the measurement of particulate solids.…
DetailsOverview In this Tech Tip, we will show you how to add a calibration standard to TRIOS software. Calibrations are obtained by comparing the literature values of known standards to the measured ones in the calibration experiment. Standards’ melting, curie, Cp, and CTE values are used for different calibrations on thermal instruments. Here we will…
DetailsWe expect a lot from our composites: rocket materials need to endure the heat of takeoff, wind turbines must withstand high wind gusts, and sneakers are expected to be durable and supportive on long runs. How do experts develop composites tailored to such specific uses and verify their properties?
DetailseBook Enhance Battery Cell Performance Through In-Operando Thermal Analysis A Guide to Predictive Thermo-Electrochemical Characterization of Battery Cells As batteries are pushed to accommodate increasing demand and new capabilities, battery research and development must keep apace with new breakthroughs without sacrificing quality. In particular, new battery chemistries need greater efficiency, safety, and stability. From choosing…
DetailsOverview TA Instruments offers recorded versions of our Theory & Applications training courses for you to watch at your convenience, whenever and wherever you are. These courses are designed to familiarize the user with an understanding of the specific TA Instrument technology, method development, operating techniques, and applications. Review the course descriptions below and enter…
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