The purpose of this paper is to provide a universally acceptable definition of “Melting” and then illustrate that loss of crystalline structure in many materials can be caused by numerous chemical processes other than thermodynamic or “True Melting”.
DetailsWe performed a comparability study of a liquid protein reference formulation using a nano differential scanning calorimeter (Nano DSC) to reveal that this thermodynamic technology detects the smallest changes in biomolecular structure in response to subtle manipulations in the reference formulation.
DetailsThe nitinol shape-memory alloy solid-solid transition is studied using differential scanning calorimetry (DSC), which reveals the reversible and hysteretic nature of this transition. This can be used to provide information on the composition of the nitinol alloy. It also serves as a tool to detect the existence of, and changes in, the intermediate R-phase.
DetailsIsothermal titration calorimetry is a technique where heat is measured under constant pressure. This heat can be translated into enthalpy based on the First Law of Thermodynamics. Although the focus of the technique has been rooted in measuring biophysical phenomena in labs that specialized in calorimetry, it has seen growth as a general technique to quantitatively describe systems from proteins to nanomaterials.
DetailsAn overview of isothermal microcalorimetry in battery research, development and quality control in order to illustrate the versatility and providing an idea of the possibilities of isothermal microcalorimetry.
DetailsThermogravimetric Analysis (TGA), which provides information about the thermal stability and decomposition rate of materials, is an excellent technique for rapidly comparing the behavior of materials tested with different flame retardants.
DetailsThe purpose of this paper is to explain and illustrate a systematic thermal analysis approach (DSC, MDSC®, and TGA) for detecting drug-excipient incompatibility and then optionally exploring the rate of reaction (kinetics) and reaction mechanism (chemistry).
DetailsAsh testing is a common technique used to determine the composition of materials. By heating a sample to high temperature in air all organic substances will pyrolyze leaving behind only inert and inorganic substances. This residue is then weighed to determine its weight percentage in the original material.
DetailsThermogravimetric Analysis (TGA), which provides information about the thermal stability and decomposition rate of materials, is an excellent technique for rapidly comparing the behavior of materials tested with different flame retardants.
DetailsThis note applies the workflow outlined in TA457 [3] to characterize coated and uncoated separators. In addition to TMA, differential scanning calorimetry (DSC), thermogravimetric analysis (TGA), and dynamic mechanical analysis (DMA) will be utilized.
DetailsIn this apps note, the properties of PLA are studied under various controlled humidity and temperature conditions.
DetailsNano Differential Scanning Calorimetry (Nano DSC) and Isothermal Titration Calorimetry (ITC) are powerful label-free and immobilization free analytic tools for thermodynamic measurements of molecular binding, biomolecular thermostability, and enzyme kinetic reactions.
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