Medical Device Testing and Characterization Workshop
TA Instruments and Waters Corporation are pleased to offer a free seminar event featuring mechanical and fatigue characterization, isothermal heat flow calorimetry, and analytical testing of extractables and leachables. The workshop will provide a working knowledge of each technique and examples of application in medical device testing and characterization. Attendees will gain practical knowledge of the measurement techniques as well as learn how the featured instrumentation and software may compliment and expand their existing laboratory capabilities.
The significance of understanding material performance in Biomedical applications can be life-critical and is often instrumental in medical device optimization or tissue mechanics research. This seminar will introduce a range of applications in which ElectroForce Mechanical Test Instruments are assisting researchers, engineers and regulatory staff. Biomaterials and tissue characterization include testing to reveal quasi-static and dynamic properties of human or animal model tissues and provide measures to assess drug-, hormone- or age-related changes in tissues such as bone, cartilage, tendon, ligament, vessels, eyes and heart valves. These properties can also be used as baseline or reference data for medical device development. Additionally, you will learn how Medical Devices undergo a range of extensive fatigue characterization to support lifetime predictions for the design, optimization and approval for safe and life-changing device solutions. Instrument demonstrations highlighting some of these test applications will also be provided.
It is now well established that the calendar life and cycle life of Li and Li-ion cells and batteries Is highly dependent upon the secondary reactions that occur between the electrodes and the cell electrolyte. These reactions are often referred to as parasitic reactions as they generally result in the loss of reversible lithium from the cell. It is now common to include a number of electrolyte additives to the cell primary electrolyte in order to improve the solid electrolyte interface (SEI) that is generally regarded as being critical for providing passivation against these parasitic reactions. Long term cycling and exposure to extraordinary temperatures have typically been employed to determine the effect of parasitic reactions and effectiveness of electrolyte additives. Techniques that can rapidly provide fundamental information on cell parasitic reactions and the effect of electrolyte chemistry in controlling the parasitic reactions are therefore of considerable value. In this presentation the use of isothermal heat flow measurements combined with high precision coulometry are explained and shown how this methodology, referred to as electrochemical calorimetry, can be very useful in discriminating the impact of electrolyte chemistry, active electrode materials and voltage cycling conditions on the calendar and cycle life characteristics of Li-ion cells.
Characterization of packaging, food contact materials, medical device components and other products is becoming increasingly important due to consumer safety concerns and more stringent global regulations. The initial step in characterizing extractables involves targeted screening, i.e. testing product extracts for known compounds. This is a well-established process and is performed using a variety of analytical techniques ranging from GC-FID-MS to LC-UV-MS. However, the final product may also contain unknown impurities present in the starting materials or degradants formed during the manufacturing process. Identifying these unknowns is typically a very complex and time-consuming process, requiring significant expertise. The UNIFI/QTof Screening Solution provides a simple workflow for both targeted screening & unknown elucidation. This UPLC, high resolution MS and comprehensive informatics platform aids in the evaluation of complex data by simplifying data review and facilitating the identification of unknown entities.
Registration for the day is free of charge and includes lunch and refreshments. To register for this event please enter your details in the form to the right.
|9:00 AM||Mechanical and Fatigue Characterization of Biomaterials and Medical Devices
Troy Nickel – Senior Product Manager, TA Instruments
|10:00 AM||Demonstrations of Mechanical and Fatigue Characterization
Luis Morales – Application Specialist, TA Instruments
|10:45 AM||Applications of Isothermal Heat Flow Calorimetry in the Evaluation of Batteries
Larry Kraus, Ph.D. – Founding Member, Cyclikal
|12:30 PM||UNIFI/QTof Screening Workflow for Confirming & Identifying Extractables & Leachables
Rich DeMuro – Principal Technical Support Specialist, Waters Corporation